7-methylthieno[3,2-d]pyrimidin-4(1H)-one

7-methylthieno[3,2-d]pyrimidin-4(1H)-one - Names and Identifiers

Name	3-Methylthieno(3,2-D)Pyrimidin-7(6H)-One
Synonyms	7-Methylthieno[3,2-d]pyrimidin-4-ol Thieno[3,2-d]pyrimidin-4-ol, 7-methyl- 7-methylthieno[3,2-d]pyrimidin-4(1H)-one 3-METHYLTHIENO(3,2-D)PYRIMIDIN-7(6H)-ONE 7-methyl-3H-thieno[3,2-d]pyrimidin-4-one 3-Methylthieno(3,2-D)Pyrimidin-7(6H)-One 7-Methylthieno[3,2-d]pyrimidin-4(1H)-one 7-Methylthieno[3,2-d]pyrimidin-4(3H)-one 4-Hydroxy-7-methylthieno[3,2-d]pyrimidine 7-methyl-3H,4H-thieno[3,2-d]pyrimidin-4-one Thieno[3,2-d]pyrimidin-4(3H)-one, 7-methyl-
CAS	175137-13-0
InChI	InChI=1/C7H6N2OS/c1-4-2-11-6-5(4)8-3-9-7(6)10/h2-3H,1H3,(H,8,9,10)

7-methylthieno[3,2-d]pyrimidin-4(1H)-one - Physico-chemical Properties

Molecular Formula	C7H6N2OS
Molar Mass	166.2
Density	1.53±0.1 g/cm3(Predicted)
Boling Point	403.9±33.0 °C(Predicted)
Flash Point	146.8°C
Vapor Presure	0.000347mmHg at 25°C
pKa	11.38±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.752

7-methylthieno[3,2-d]pyrimidin-4(1H)-one - Introduction

3-Methylthieno (3,2-d) Pyrimidin-7(6h)-One, also known as MTT(3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazole), is an organic compound. Its properties are as follows:

1. Chemical formula: C15H12N2OS
2. Appearance: white to light yellow crystal powder
3. Melting Point: 186-189 C
4. Solubility: soluble in most organic solvents, slightly soluble in water

MTT is commonly used in cytotoxicity and cell proliferation experiments. It can be used as a marker for cell viability and proliferation, and the metabolic activity of cells can be evaluated by measuring the amount of toluamine salt formed by reduced MTT in the cells. In addition, MTT can also be used to detect cellular respiratory function and enzyme activity in cells, which is widely used in the study of drug activity, toxicology and biological processes.

The preparation method of MTT can be synthesized by the reaction of aniline and dimethyl thiourea. The specific preparation process involves multiple steps such as the protection of aniline, the substitution and ring-closing of thiourea.

Regarding safety information, MTT is relatively safe under general conditions of use, but the following items should also be paid attention:
1. Sealed storage: avoid exposure to light and moisture, because MTT is sensitive to light and moisture.
2. Avoid contact with skin and eyes: when using, should wear gloves and goggles, avoid direct contact with skin and eyes.
3. Read the safety instructions before use: before using MTT, read the relevant safety instructions in detail and operate in accordance with the operating instructions.
4. Waste disposal: Waste should be disposed of properly in accordance with local regulations and regulations.

In General, MTT is an organic compound commonly used in cell biology experiments. It has certain toxicity and sensitivity. It needs to comply with safe operating procedures when used.

Last Update：2024-04-09 19:05:47